› 1biv

Solution NMR

BOVINE IMMUNODEFICIENCY VIRUS TAT-TAR COMPLEX, NMR, 5 STRUCTURES

Released:
DOI: 10.2210/pdb1biv/pdb
PDB entry 1biv coloured by chain, ensemble of 5 models, front view.
PDB entry 1biv coloured by chain, ensemble of 5 models, side view.
PDB entry 1biv coloured by chain, ensemble of 5 models, top view.
Source organisms:
Primary publication:
Molecular recognition in the bovine immunodeficiency virus Tat peptide-TAR RNA complex.
Ye X, Kumar RA, Patel DJ
Chem Biol 2 827-40 (1995)
PMID: 8807816

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Structure domain:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-148644 (preferred)
Entry contents:
1 distinct polypeptide molecule
1 distinct RNA molecule
Macromolecules (2 distinct):
Protein Tat Chain: B
Molecule details ›
Chain: B
Length: 17 amino acids
Theoretical weight: 1.97 KDa
Source organism: Bovine immunodeficiency virus
Expression system: Not provided
UniProt:
  • Canonical: P19564 (Residues: 65-81; Coverage: 17%)
Gene name: tat
TAR RNA Chain: A
Molecule details ›
Chain: A
Length: 28 nucleotides
Theoretical weight: 8.92 KDa
Source organism: synthetic construct
Expression system: Not provided

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: molecular dynamics
Expression system: Not provided

Quick links

Citations

24 review citations

Intrinsically unstructured proteins: re-assessing the protein structure-function paradigm.
Wright et al. (1999)
23 more

12 mentions without citation

Face-time with TAR: Portraits of an HIV-1 RNA with diverse modes of effector recognition relevant for drug discovery.
Chavali et al. (2019)
11 more