› 1bnb

Solution NMR

SOLUTION STRUCTURE OF BOVINE NEUTROPHIL BETA-DEFENSIN 12: THE PEPTIDE FOLD OF THE BETA-DEFENSINS IS IDENTICAL TO THAT OF THE CLASSICAL DEFENSINS

Released:
DOI: 10.2210/pdb1bnb/pdb
PDB entry 1bnb coloured by chain, ensemble of 20 models, front view.
PDB entry 1bnb coloured by chain, ensemble of 20 models, side view.
PDB entry 1bnb coloured by chain, ensemble of 20 models, top view.
Source organism: Bos taurus
Primary publication:
Solution structure of bovine neutrophil beta-defensin-12: the peptide fold of the beta-defensins is identical to that of the classical defensins.
Zimmermann GR, Legault P, Selsted ME, Pardi A
Biochemistry 34 13663-71 (1995)
PMID: 7577957

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-155446 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Beta-defensin 12 Chain: A
Molecule details ›
Chain: A
Length: 38 amino acids
Theoretical weight: 4.13 KDa
Source organism: Bos taurus
UniProt:
  • Canonical: P46170 (Residues: 1-38; Coverage: 100%)
Gene name: DEFB12
Sequence domains: Beta defensin

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores

Quick links

Citations

29 review citations

Defensins: antimicrobial peptides of innate immunity.
Ganz T. (2003)
28 more

6 mentions without citation

De novo design of antimicrobial polymers, foldamers, and small molecules: from discovery to practical applications.
Tew et al. (2010)
5 more