› 1bw7

Solution NMR

SOLUTION STRUCTURE OF A DNA DUPLEX CONTAINING A REPLICABLE DIFLUOROTOLUENE-ADENINE PAIR

Released:
DOI: 10.2210/pdb1bw7/pdb
PDB entry 1bw7 coloured by chain, front view.
PDB entry 1bw7 coloured by chain, side view.
PDB entry 1bw7 coloured by chain, top view.
Source organism: Synthetic construct
Primary publication:
Solution structure of a DNA duplex containing a replicable difluorotoluene-adenine pair.
Guckian KM, Krugh TR, Kool ET
Nat Struct Biol 5 954-9 (1998)
PMID: 9808039

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-113515 (preferred)
Entry contents:
2 distinct DNA molecules
Macromolecules (2 distinct):
DNA (5'-D(*CP*GP*CP*AP*TP*(DFT)P*GP*TP*TP*AP*CP*C)-3') Chain: A
Molecule details ›
Chain: A
Length: 12 nucleotides
Theoretical weight: 3.62 KDa
Source organism: Synthetic construct
Expression system: Not provided
DNA (5'-D(*GP*GP*TP*AP*AP*CP*AP*AP*TP*GP*CP*G)-3') Chain: B
Molecule details ›
Chain: B
Length: 12 nucleotides
Theoretical weight: 3.71 KDa
Source organism: Synthetic construct
Expression system: Not provided

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: RESTRAINED MOLECULAR DYNAMICS
Expression system: Not provided

Quick links

Citations

15 review citations

DNA replication fidelity.
Kunkel et al. (2000)
14 more

1 mention without citation

Expanding the horizon of the thymine isostere biochemistry: unique cyclobutane dimers formed by photoreaction between a thymine and a toluene residue in the dinucleotide framework.
Liu et al. (2012)