Function and Biology Details
Reaction catalysed:
ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate
Biochemical function:
- not assigned
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-108683 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
AP-2 complex subunit mu
Molecule details ›
Chain: A
Length: 321 amino acids
Theoretical weight: 36.71 KDa
Source organism: Rattus norvegicus
Expression system: Escherichia coli BL21
UniProt:
Sequence domains: Adaptor complexes medium subunit family
Structure domains: Mu homology domain, subdomain B
Length: 321 amino acids
Theoretical weight: 36.71 KDa
Source organism: Rattus norvegicus
Expression system: Escherichia coli BL21
UniProt:
- Canonical:
P84092 (Residues: 120-435; Coverage: 73%)
Sequence domains: Adaptor complexes medium subunit family
Structure domains: Mu homology domain, subdomain B
receptor protein-tyrosine kinase
Molecule details ›
Chain: P
Length: 6 amino acids
Theoretical weight: 801 Da
Source organism: Rattus norvegicus
Expression system: Not provided
UniProt:
Length: 6 amino acids
Theoretical weight: 801 Da
Source organism: Rattus norvegicus
Expression system: Not provided
UniProt:
- Canonical: A8IP97 (Residues: 139-144; Coverage: 3%)
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
SRS BEAMLINE PX7.2
Spacegroup:
P64
Expression systems:
- Escherichia coli BL21
- Not provided
