› 1bwm

Solution NMR

A SINGLE-CHAIN T CELL RECEPTOR

Released:
DOI: 10.2210/pdb1bwm/pdb
PDB entry 1bwm coloured by chain, ensemble of 15 models, front view.
PDB entry 1bwm coloured by chain, ensemble of 15 models, side view.
PDB entry 1bwm coloured by chain, ensemble of 15 models, top view.
Source organism: Mus musculus
Primary publication:
Structure, specificity and CDR mobility of a class II restricted single-chain T-cell receptor.
Hare BJ, Wyss DF, Osburne MS, Kern PS, Reinherz EL, Wagner G
Nat Struct Biol 6 574-81 (1999)
PMID: 10360364

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-212320 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Ig-like domain-containing protein Chain: A
Molecule details ›
Chain: A
Length: 249 amino acids
Theoretical weight: 26.97 KDa
Source organism: Mus musculus
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q5R1G1 (Residues: 29-121; Coverage: 93%)
Gene name: TRAV14D-2
Sequence domains: Immunoglobulin V-set domain
Structure domains: Immunoglobulins

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: molecular dynamics
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

15 review citations

T cell antigen receptor recognition of antigen-presenting molecules.
Rossjohn et al. (2015)
14 more

2 mentions without citation

Conformational changes and flexibility in T-cell receptor recognition of peptide-MHC complexes.
Armstrong et al. (2008)
1 more