› 1byy

Solution NMR

SODIUM CHANNEL IIA INACTIVATION GATE

Released:
DOI: 10.2210/pdb1byy/pdb
PDB entry 1byy coloured by chain, ensemble of 10 models, front view.
PDB entry 1byy coloured by chain, ensemble of 10 models, side view.
PDB entry 1byy coloured by chain, ensemble of 10 models, top view.
Source organism: Rattus norvegicus
Primary publication:
Solution structure of the sodium channel inactivation gate.
Rohl CA, Boeckman FA, Baker C, Scheuer T, Catterall WA, Klevit RE
Biochemistry 38 855-61 (1999)
PMID: 9893979

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-138169 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Sodium channel protein type 2 subunit alpha Chain: A
Molecule details ›
Chain: A
Length: 53 amino acids
Theoretical weight: 6.27 KDa
Source organism: Rattus norvegicus
Expression system: Escherichia coli
UniProt:
  • Canonical: P04775 (Residues: 1474-1526; Coverage: 3%)
Gene names: Scn2a, Scn2a1

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: DISTANCE GEOMETRY, SIMULATED ANNEALING
Expression system: Escherichia coli

Quick links

Citations

30 review citations

From ionic currents to molecular mechanisms: the structure and function of voltage-gated sodium channels.
Catterall WA. (2000)
29 more

7 mentions without citation

Seeing the forest through the trees: towards a unified view on physiological calcium regulation of voltage-gated sodium channels.
Van Petegem et al. (2012)
6 more