› 1bzv

Solution NMR

[D-ALAB26]-DES(B27-B30)-INSULIN-B26-AMIDE A SUPERPOTENT SINGLE-REPLACEMENT INSULIN ANALOGUE, NMR, MINIMIZED AVERAGE STRUCTURE

Released:
DOI: 10.2210/pdb1bzv/pdb
PDB entry 1bzv coloured by chain, front view.
PDB entry 1bzv coloured by chain, side view.
PDB entry 1bzv coloured by chain, top view.
Source organisms:
Primary publication:
The solution structure of a superpotent B-chain-shortened single-replacement insulin analogue.
Kurapkat G, Siedentop M, Gattner HG, Hagelstein M, Brandenburg D, Grötzinger J, Wollmer A
Protein Sci 8 499-508 (1999)
PMID: 10091652

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-151719 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
INSULIN Chain: A
Molecule details ›
Chain: A
Length: 21 amino acids
Theoretical weight: 2.38 KDa
Source organism: Balaenoptera physalus
Expression system: Not provided
Insulin B chain Chain: B
Molecule details ›
Chain: B
Length: 26 amino acids
Theoretical weight: 2.91 KDa
Source organism: synthetic construct
Expression system: Not provided
UniProt:
  • Canonical: P30410 (Residues: 25-49; Coverage: 29%)
Gene name: INS

Ligands and Environments

No bound ligands
1 modified residue:
Ligand DAL 1 x DAL

Experiments and Validation Details

Entry percentile scores
Refinement method: distance geometry
Expression system: Not provided

Quick links

Citations

2 review citations

Insulin structure and function.
Mayer et al. (2007)
1 more