› 1c11

Solution NMR

INTERCALATED D(TCCCGTTTCCA) DIMER, NMR, 7 STRUCTURES

Released:
DOI: 10.2210/pdb1c11/pdb
PDB entry 1c11 coloured by chain, ensemble of 7 models, front view.
PDB entry 1c11 coloured by chain, ensemble of 7 models, side view.
PDB entry 1c11 coloured by chain, ensemble of 7 models, top view.
Source organism: Synthetic construct
Primary publication:
Centromeric pyrimidine strands fold into an intercalated motif by forming a double hairpin with a novel T:G:G:T tetrad: solution structure of the d(TCCCGTTTCCA) dimer.
Gallego J, Chou SH, Reid BR
J Mol Biol 273 840-56 (1997)
PMID: 9367776

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-113522 (preferred)
Entry contents:
1 distinct DNA molecule
Macromolecule:
DNA (5'-D(*TP*CP*CP*CP*GP*TP*TP*TP*CP*CP*A)-3') Chains: A, B
Molecule details ›
Chains: A, B
Length: 11 nucleotides
Theoretical weight: 3.26 KDa
Source organism: Synthetic construct
Expression system: Not provided

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: NOESY BACKC.+DG+MD
Expression system: Not provided

Quick links

Citations

5 review citations

Multistranded DNA structures.
Gilbert et al. (1999)
4 more

35 mentions without citation

Development of second-generation VEGFR tyrosine kinase inhibitors: current status.
Bhargava et al. (2011)
34 more