› 1cb3

Solution NMR

LOCAL INTERACTIONS DRIVE THE FORMATION OF NON-NATIVE STRUCTURE IN THE DENATURED STATE OF HUMAN ALPHA-LACTALBUMIN: A HIGH RESOLUTION STRUCTURAL CHARACTERIZATION OF A PEPTIDE MODEL IN AQUEOUS SOLUTION

Released:
DOI: 10.2210/pdb1cb3/pdb
PDB entry 1cb3 coloured by chain, ensemble of 40 models, front view.
PDB entry 1cb3 coloured by chain, ensemble of 40 models, side view.
PDB entry 1cb3 coloured by chain, ensemble of 40 models, top view.
Source organism: Homo sapiens
Primary publication:
Local interactions drive the formation of nonnative structure in the denatured state of human alpha-lactalbumin: a high resolution structural characterization of a peptide model in aqueous solution.
Demarest SJ, Hua Y, Raleigh DP
Biochemistry 38 7380-7 (1999)
PMID: 10353850

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-132931 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Alpha-lactalbumin Chain: A
Molecule details ›
Chain: A
Length: 13 amino acids
Theoretical weight: 1.33 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P00709 (Residues: 120-129; Coverage: 8%)
Gene names: LALBA, LYZL7

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: DISTANCE GEOMETRY AND SIMULATED ANNEALING
Expression system: Not provided

Quick links

Citations

18 citation in other articles

The protein folding network.
Rao et al. (2004)
17 more

2 mentions without citation

A hybrid, bottom-up, structurally accurate, Go¯-like coarse-grained protein model.
Sanyal et al. (2019)
1 more