› 1cew

X-ray diffraction
2Å resolution

THE 2.0 ANGSTROMS X-RAY CRYSTAL STRUCTURE OF CHICKEN EGG WHITE CYSTATIN AND ITS POSSIBLE MODE OF INTERACTION WITH CYSTEINE PROTEINASES

Released:
DOI: 10.2210/pdb1cew/pdb
PDB entry 1cew coloured by chain, front view.
PDB entry 1cew coloured by chain, side view.
PDB entry 1cew coloured by chain, top view.
Source organism: Gallus gallus
Primary publication:
The 2.0 A X-ray crystal structure of chicken egg white cystatin and its possible mode of interaction with cysteine proteinases.
Bode W, Engh R, Musil D, Thiele U, Huber R, Karshikov A, Brzin J, Kos J, Turk V
EMBO J 7 2593-9 (1988)
PMID: 3191914

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-133892 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Cystatin Chain: I
Molecule details ›
Chain: I
Length: 108 amino acids
Theoretical weight: 12.2 KDa
Source organism: Gallus gallus
Expression system: Not provided
UniProt:
  • Canonical: P01038 (Residues: 32-139; Coverage: 93%)
Sequence domains: Cystatin domain
Structure domains: Nuclear Transport Factor 2; Chain: A,

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: P3121
Unit cell:
a: 47.9Å b: 47.9Å c: 87.5Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.198 0.198 not available
Expression system: Not provided

Quick links

Citations

55 review citations

Natural protein proteinase inhibitors and their interaction with proteinases.
Bode et al. (1992)
54 more

33 mentions without citation

Chemerin regulation and role in host defense.
Zabel et al. (2014)
32 more