› 1co0

Solution NMR

NMR STUDY OF TRP REPRESSOR-MTR OPERATOR DNA COMPLEX

Released:
DOI: 10.2210/pdb1co0/pdb
PDB entry 1co0 coloured by chain, ensemble of 15 models, front view.
PDB entry 1co0 coloured by chain, ensemble of 15 models, side view.
PDB entry 1co0 coloured by chain, ensemble of 15 models, top view.
Source organism: Escherichia coli
Primary publication:
Allostery and Induced Fit, NMR and Molecular Modeling Study of the trp-repressor - mtr DNA complex
Brocchieri L, Zhou GP, Jardetzky O
Structures and Mechanisms, ACS Symposium Series 827 340-366 (2002)

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
hetero tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-113550 (preferred)
Entry contents:
1 distinct polypeptide molecule
2 distinct DNA molecules
Macromolecules (3 distinct):
Trp operon repressor Chains: A, B
Molecule details ›
Chains: A, B
Length: 107 amino acids
Theoretical weight: 12.24 KDa
Source organism: Escherichia coli
Expression system: Escherichia coli
UniProt:
  • Canonical: P0A881 (Residues: 2-108; Coverage: 99%)
Gene names: JW4356, b4393, rtrY, trpR
Sequence domains: Trp repressor protein
Structure domains: TrpR-like
5'-D(*TP*GP*TP*AP*CP*TP*CP*GP*TP*GP*TP*AP*CP*TP*GP*GP*TP*AP*CP*A)-3' Chain: E
Molecule details ›
Chain: E
Length: 20 nucleotides
Theoretical weight: 6.14 KDa
Source organism: Escherichia coli
Expression system: Not provided
5'-D(*TP*GP*TP*AP*CP*CP*AP*GP*TP*AP*CP*AP*CP*GP*AP*GP*TP*AP*CP*A)-3' Chain: F
Molecule details ›
Chain: F
Length: 20 nucleotides
Theoretical weight: 6.13 KDa
Source organism: Escherichia coli
Expression system: Not provided

Ligands and Environments

1 bound ligand:
Ligand TRP 2 x TRP
No modified residues

Experiments and Validation Details

Entry percentile scores
Expression systems:
  • Escherichia coli
  • Not provided

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