› 1csn

X-ray diffraction
2Å resolution

BINARY COMPLEX OF CASEIN KINASE-1 WITH MGATP

Released:
DOI: 10.2210/pdb1csn/pdb
PDB entry 1csn coloured by chain, front view.
PDB entry 1csn coloured by chain, side view.
PDB entry 1csn coloured by chain, top view.
Source organism: Schizosaccharomyces pombe
Primary publication:
Crystal structure of casein kinase-1, a phosphate-directed protein kinase.
Xu RM, Carmel G, Sweet RM, Kuret J, Cheng X
EMBO J 14 1015-23 (1995)
PMID: 7889932

Function and Biology Details

Reaction catalysed: 
ATP + a protein = ADP + a phosphoprotein
Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-154060 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Casein kinase I homolog 1 Chain: A
Molecule details ›
Chain: A
Length: 298 amino acids
Theoretical weight: 34.38 KDa
Source organism: Schizosaccharomyces pombe
UniProt:
  • Canonical: P40233 (Residues: 1-298; Coverage: 67%)
Gene names: SPBC1347.06c, cki1
Sequence domains: Protein kinase domain
Structure domains:

Ligands and Environments

3 bound ligands:
Ligand MG 1 x MG
Ligand SO4 2 x SO4
Ligand ATP 1 x ATP
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X12C
Spacegroup: P3221
Unit cell:
a: 78.96Å b: 78.96Å c: 120.38Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.207 0.207 not available

Quick links

Citations

22 review citations

Active and inactive protein kinases: structural basis for regulation.
Johnson et al. (1996)
21 more

28 mentions without citation

Sequence-structure analysis of FAD-containing proteins.
Dym et al. (2001)
27 more