› 1cts

X-ray diffraction
2.7Å resolution

CRYSTALLOGRAPHIC REFINEMENT AND ATOMIC MODELS OF TWO DIFFERENT FORMS OF CITRATE SYNTHASE AT 2.7 AND 1.7 ANGSTROMS RESOLUTION

Released:
DOI: 10.2210/pdb1cts/pdb
PDB entry 1cts coloured by chain, front view.
PDB entry 1cts coloured by chain, side view.
PDB entry 1cts coloured by chain, top view.
Source organism: Sus scrofa
Primary publication:
Crystallographic refinement and atomic models of two different forms of citrate synthase at 2.7 and 1.7 A resolution.
Remington S, Wiegand G, Huber R
J Mol Biol 158 111-52 (1982)
PMID: 7120407

Function and Biology Details

Reaction catalysed: 
Acetyl-CoA + H(2)O + oxaloacetate = citrate + CoA
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-133671 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Citrate synthase, mitochondrial Chain: A
Molecule details ›
Chain: A
Length: 437 amino acids
Theoretical weight: 48.98 KDa
Source organism: Sus scrofa
Expression system: Not provided
UniProt:
  • Canonical: P00889 (Residues: 28-464; Coverage: 94%)
Gene name: CS
Sequence domains: Citrate synthase, C-terminal domain
Structure domains:

Ligands and Environments

1 bound ligand:
Ligand CIT 1 x CIT
No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: P41212
Unit cell:
a: 77.4Å b: 77.4Å c: 196.4Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.183 0.183 not available
Expression system: Not provided

Quick links

Citations

28 review citations

3D domain swapping: as domains continue to swap.
Liu et al. (2002)
27 more

21 mentions without citation

The UNC-45 myosin chaperone: from worms to flies to vertebrates.
Lee et al. (2014)
20 more