› 1cxn

Solution NMR

REFINED THREE-DIMENSIONAL SOLUTION STRUCTURE OF A SNAKE CARDIOTOXIN: ANALYSIS OF THE SIDE-CHAIN ORGANISATION SUGGESTS THE EXISTENCE OF A POSSIBLE PHOSPHOLIPID BINDING SITE

Released:
DOI: 10.2210/pdb1cxn/pdb
PDB entry 1cxn coloured by chain, front view.
PDB entry 1cxn coloured by chain, side view.
PDB entry 1cxn coloured by chain, top view.
Source organism: Naja nigricollis
Primary publication:
Refined three-dimensional solution structure of a snake cardiotoxin: analysis of the side-chain organization suggests the existence of a possible phospholipid binding site.
Gilquin B, Roumestand C, Zinn-Justin S, Ménez A, Toma F
Biopolymers 33 1659-75 (1993)
PMID: 8241426

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-134322 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Cytotoxin 1 Chain: A
Molecule details ›
Chain: A
Length: 60 amino acids
Theoretical weight: 6.84 KDa
Source organism: Naja nigricollis
Expression system: Not provided
UniProt:
  • Canonical: P01468 (Residues: 1-60; Coverage: 100%)
Structure domains: CD59

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Expression system: Not provided

Quick links

Citations

2 review citations

Snake venom cardiotoxins-structure, dynamics, function and folding.
Kumar et al. (1997)
1 more

1 mention without citation

Motions and structural variability within toxins: implication for their use as scaffolds for protein engineering.
Gilquin et al. (2003)