› 1d0w

Solution NMR

SOLUTION STRUCTURE OF LACTAM-BRIDGED C-TERMINAL ANALOGUE-I OF NEUROPEPTIDE Y

Released:
DOI: 10.2210/pdb1d0w/pdb
PDB entry 1d0w coloured by chain, ensemble of 20 models, front view.
PDB entry 1d0w coloured by chain, ensemble of 20 models, side view.
PDB entry 1d0w coloured by chain, ensemble of 20 models, top view.
Source organism: Synthetic construct
Primary publication:
Stabilization of the helical structure of Y2-selective analogues of neuropeptide Y by lactam bridges.
Yao S, Smith-White MA, Potter EK, Norton RS
J Med Chem 45 2310-8 (2002)
PMID: 12014969

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-162149 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
C-TERMINAL ANALOGUE OF NEUROPEPTIDE Y, A POTENT Y2 RECEPTOR AGONIST Chain: A
Molecule details ›
Chain: A
Length: 14 amino acids
Theoretical weight: 1.79 KDa
Source organism: Synthetic construct
Expression system: Not provided

Ligands and Environments

No bound ligands
1 modified residue:
Ligand AYA 1 x AYA

Experiments and Validation Details

Entry percentile scores
Refinement method: simulated annealing
Expression system: Not provided

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Citations

4 review citations

Mu-conotoxins as leads in the development of new analgesics.
Norton RS. (2010)
3 more