› 1d14

X-ray diffraction
1.5Å resolution

STRUCTURE OF 11-DEOXYDAUNOMYCIN BOUND TO DNA CONTAINING A PHOSPHOROTHIOATE

Released:
DOI: 10.2210/pdb1d14/pdb
PDB entry 1d14 coloured by chain, front view.
PDB entry 1d14 coloured by chain, side view.
PDB entry 1d14 coloured by chain, top view.
Source organism: Synthetic construct
Primary publication:
Structure of 11-deoxydaunomycin bound to DNA containing a phosphorothioate.
Williams LD, Egli M, Ughetto G, van der Marel GA, van Boom JH, Quigley GJ, Wang AH, Rich A, Frederick CA
J Mol Biol 215 313-20 (1990)
PMID: 2152325

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-113574 (preferred)
Entry contents:
1 distinct DNA molecule
Macromolecule:
DNA (5'-D(*CP*GP*TP*(AS)P*CP*G)-3') Chain: A
Molecule details ›
Chain: A
Length: 6 nucleotides
Theoretical weight: 1.83 KDa
Source organism: Synthetic construct
Expression system: Not provided

Ligands and Environments

1 bound ligand:
Ligand DM3 1 x DM3
1 modified residue:
Ligand AS 1 x AS

Experiments and Validation Details

Entry percentile scores
Spacegroup: P2
Unit cell:
a: 17.73Å b: 19.13Å c: 26.36Å
α: 90° β: 98.01° γ: 90°
R-values:
R R work R free
0.224 not available not available
Expression system: Not provided

Quick links

Citations

1 review citation

Crystallographic studies of chemically modified nucleic acids: a backward glance.
Egli et al. (2010)
10 other articles

4 mentions without citation

DNA conformations and their sequence preferences.
Svozil et al. (2008)
3 more