› 1d2m

X-ray diffraction
1.9Å resolution

UVRB PROTEIN OF THERMUS THERMOPHILUS HB8; A NUCLEOTIDE EXCISION REPAIR ENZYME

Released:
DOI: 10.2210/pdb1d2m/pdb
PDB entry 1d2m coloured by chain, front view.
PDB entry 1d2m coloured by chain, side view.
PDB entry 1d2m coloured by chain, top view.
Source organism: Thermus thermophilus HB8
Primary publication:
Crystal structure of Thermus thermophilus HB8 UvrB protein, a key enzyme of nucleotide excision repair.
Nakagawa N, Sugahara M, Masui R, Kato R, Fukuyama K, Kuramitsu S
J Biochem 126 986-90 (1999)
PMID: 10578047

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-176340 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
UvrABC system protein B Chain: A
Molecule details ›
Chain: A
Length: 665 amino acids
Theoretical weight: 76.27 KDa
Source organism: Thermus thermophilus HB8
Expression system: Escherichia coli
UniProt:
  • Canonical: Q56243 (Residues: 1-665; Coverage: 100%)
Gene names: TTHA1892, uvrB
Sequence domains:
Structure domains:

Ligands and Environments

2 bound ligands:
Ligand BOG 3 x BOG
Ligand SO4 1 x SO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SPRING-8 BEAMLINE BL41XU
Spacegroup: P3221
Unit cell:
a: 135.04Å b: 135.04Å c: 106.756Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.234 0.234 0.253
Expression system: Escherichia coli

Quick links

Citations

6 review citations

Helicase structure and mechanism.
Caruthers et al. (2002)
5 more

7 mentions without citation

Prokaryotic nucleotide excision repair.
Kisker et al. (2013)
6 more