› 1d32

X-ray diffraction
1.7Å resolution

DRUG-INDUCED DNA REPAIR: X-RAY STRUCTURE OF A DNA-DITERCALINIUM COMPLEX

Released:
DOI: 10.2210/pdb1d32/pdb
PDB entry 1d32 coloured by chain, front view.
PDB entry 1d32 coloured by chain, side view.
PDB entry 1d32 coloured by chain, top view.
Source organism: Synthetic construct
Primary publication:
Drug-induced DNA repair: X-ray structure of a DNA-ditercalinium complex.
Gao Q, Williams LD, Egli M, Rabinovich D, Chen SL, Quigley GJ, Rich A
Proc Natl Acad Sci U S A 88 2422-6 (1991)
PMID: 2006181

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-113593 (preferred)
Entry contents:
1 distinct DNA molecule
Macromolecule:
DNA (5'-D(*CP*GP*CP*G)-3') Chains: A, B
Molecule details ›
Chains: A, B
Length: 4 nucleotides
Theoretical weight: 1.19 KDa
Source organism: Synthetic construct
Expression system: Not provided

Ligands and Environments

1 bound ligand:
Ligand DIT 1 x DIT
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RU200
Spacegroup: P41212
Unit cell:
a: 26.88Å b: 26.88Å c: 82.6Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.225 not available not available
Expression system: Not provided

Quick links

Citations

6 review citations

Noncovalent interactions with DNA: an overview.
Strekowski et al. (2007)
5 more

7 mentions without citation

Structure-based DNA-targeting strategies with small molecule ligands for drug discovery.
Sheng et al. (2013)
6 more