› 1d4r

X-ray diffraction
2Å resolution

29-mer fragment of human srp rna helix 6

Released:
DOI: 10.2210/pdb1d4r/pdb
PDB entry 1d4r coloured by chain, front view.
PDB entry 1d4r coloured by chain, side view.
PDB entry 1d4r coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
The 2 A structure of helix 6 of the human signal recognition particle RNA.
Wild K, Weichenrieder O, Leonard GA, Cusack S
Structure 7 1345-52 (1999)
PMID: 10574798

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assemblies composition:
hetero dimer (preferred)
homo dimer
Assembly name:
PDBe Complex ID:
PDB-CPX-195988 (preferred)
Entry contents:
2 distinct RNA molecules
Macromolecules (2 distinct):
29-MER OF MODIFIED SRP RNA HELIX 6 Chain: A
Molecule details ›
Chain: A
Length: 29 nucleotides
Theoretical weight: 9.55 KDa
Source organism: Homo sapiens
Expression system: Not provided
29-MER OF MODIFIED SRP RNA HELIX 6 Chains: B, C
Molecule details ›
Chains: B, C
Length: 29 nucleotides
Theoretical weight: 9.49 KDa
Source organism: Homo sapiens
Expression system: Not provided

Ligands and Environments

1 bound ligand:
Ligand MG 5 x MG
2 modified residues:
Ligand GDP 3 x GDP
Ligand A23 1 x A23

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-4
Spacegroup: P3121
Unit cell:
a: 42.98Å b: 42.98Å c: 231.42Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.275 0.264 0.288
Expression system: Not provided

Quick links

Citations

3 review citations

RNA folding: beyond Watson-Crick pairs.
Westhof et al. (2000)
2 more

9 mentions without citation

Mutations in Plasmodium falciparum cytochrome b that are associated with atovaquone resistance are located at a putative drug-binding site.
Korsinczky et al. (2000)
8 more