› 1d87

X-ray diffraction
2.25Å resolution

CONFORMATIONAL INFLUENCE OF THE RIBOSE 2'-HYDROXYL GROUP: CRYSTAL STRUCTURES OF DNA-RNA CHIMERIC DUPLEXES

Released:
DOI: 10.2210/pdb1d87/pdb
PDB entry 1d87 coloured by chain, front view.
PDB entry 1d87 coloured by chain, side view.
PDB entry 1d87 coloured by chain, top view.
Source organism: Synthetic construct
Primary publication:
Conformational influence of the ribose 2'-hydroxyl group: crystal structures of DNA-RNA chimeric duplexes.
Egli M, Usman N, Rich A
Biochemistry 32 3221-37 (1993)
PMID: 7681688

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-113053 (preferred)
Entry contents:
1 distinct DNA/RNA hybrid molecule
Macromolecule:
DNA/RNA (5'-R(*GP*)-D(*CP*GP*TP*AP*TP*AP*CP*GP*C)-3') Chains: A, B
Molecule details ›
Chains: A, B
Length: 10 nucleotides
Theoretical weight: 3.06 KDa
Source organism: Synthetic construct
Expression system: Not provided

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: P212121
Unit cell:
a: 27.5Å b: 44.23Å c: 44.61Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.178 not available not available
Expression system: Not provided

Quick links

Citations

19 review citations

Unlocking the sugar "steric gate" of DNA polymerases.
Brown et al. (2011)
18 more

1 mention without citation

Crystal structure of RNA-DNA duplex provides insight into conformational changes induced by RNase H binding.
Davis et al. (2015)