› 1dcq

X-ray diffraction
2.1Å resolution

CRYSTAL STRUCTURE OF THE ARF-GAP DOMAIN AND ANKYRIN REPEATS OF PAPBETA.

Released:
DOI: 10.2210/pdb1dcq/pdb
PDB entry 1dcq coloured by chain, front view.
PDB entry 1dcq coloured by chain, side view.
PDB entry 1dcq coloured by chain, top view.
Source organism: Mus musculus
Primary publication:
Crystal structure of the ARF-GAP domain and ankyrin repeats of PYK2-associated protein beta.
Mandiyan V, Andreev J, Schlessinger J, Hubbard SR
EMBO J 18 6890-8 (1999)
PMID: 10601011

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:
Structure domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-181982 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 2 Chain: A
Molecule details ›
Chain: A
Length: 278 amino acids
Theoretical weight: 30.89 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
  • Canonical: Q7SIG6 (Residues: 420-697; Coverage: 29%)
Gene names: Asap2, Ddef2, Gm1523, Gm592
Sequence domains:
Structure domains:

Ligands and Environments

1 bound ligand:
Ligand ZN 1 x ZN
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X4A
Spacegroup: C2221
Unit cell:
a: 73.935Å b: 132.208Å c: 59.817Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.23 0.213 0.266
Expression system: Escherichia coli

Quick links

Citations

16 review citations

Small GTP-binding proteins.
Takai et al. (2001)
15 more

10 mentions without citation

A primer on ankyrin repeat function in TRP channels and beyond.
Gaudet R. (2008)
9 more