› 1den

Solution NMR

PROTEINASE INHIBITOR HOMOLOGUES AS POTASSIUM CHANNEL BLOCKERS

Released:
DOI: 10.2210/pdb1den/pdb
PDB entry 1den coloured by chain, ensemble of 29 models, front view.
PDB entry 1den coloured by chain, ensemble of 29 models, side view.
PDB entry 1den coloured by chain, ensemble of 29 models, top view.
Source organism: Dendroaspis polylepis polylepis
Primary publication:
Proteinase inhibitor homologues as potassium channel blockers.
Lancelin JM, Foray MF, Poncin M, Hollecker M, Marion D
Nat Struct Biol 1 246-50 (1994)
PMID: 7544683

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-133767 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Kunitz-type serine protease inhibitor homolog dendrotoxin I Chain: A
Molecule details ›
Chain: A
Length: 60 amino acids
Theoretical weight: 7.17 KDa
Source organism: Dendroaspis polylepis polylepis
Expression system: Not provided
UniProt:
  • Canonical: P00979 (Residues: 1-60; Coverage: 100%)
Sequence domains: Kunitz/Bovine pancreatic trypsin inhibitor domain
Structure domains: Pancreatic trypsin inhibitor Kunitz domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Expression system: Not provided

Quick links

Citations

8 review citations

Twenty years of dendrotoxins.
Harvey AL. (2001)
7 more

2 mentions without citation

The Kunitz-Type Protein ShPI-1 Inhibits Serine Proteases and Voltage-Gated Potassium Channels.
García-Fernández et al. (2016)
1 more