› 1dhm

Solution NMR

DNA-BINDING DOMAIN OF E2 FROM HUMAN PAPILLOMAVIRUS-31, NMR, MINIMIZED AVERAGE STRUCTURE

Released:
DOI: 10.2210/pdb1dhm/pdb
PDB entry 1dhm coloured by chain, front view.
PDB entry 1dhm coloured by chain, side view.
PDB entry 1dhm coloured by chain, top view.
Source organism: human papillomavirus 31
Primary publication:
Solution structure of the DNA-binding domain of a human papillomavirus E2 protein: evidence for flexible DNA-binding regions.
Liang H, Petros AM, Meadows RP, Yoon HS, Egan DA, Walter K, Holzman TF, Robins T, Fesik SW
Biochemistry 35 2095-103 (1996)
PMID: 8652551

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-148047 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Regulatory protein E2 Chains: A, B
Molecule details ›
Chains: A, B
Length: 83 amino acids
Theoretical weight: 9.52 KDa
Source organism: human papillomavirus 31
Expression system: Escherichia coli
UniProt:
  • Canonical: P17383 (Residues: 291-372; Coverage: 22%)
Gene name: E2
Sequence domains: E2 (early) protein, C terminal
Structure domains: Alpha-Beta Plaits

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Expression system: Escherichia coli

Quick links

Citations

6 review citations

The papillomavirus E2 proteins: structure, function, and biology.
Hegde RS. (2002)
5 more

3 mentions without citation

The papillomavirus E2 proteins.
McBride AA. (2013)
2 more