› 1dm5

X-ray diffraction
1.93Å resolution

ANNEXIN XII E105K HOMOHEXAMER CRYSTAL STRUCTURE

Released:
DOI: 10.2210/pdb1dm5/pdb
PDB entry 1dm5 coloured by chain, front view.
PDB entry 1dm5 coloured by chain, side view.
PDB entry 1dm5 coloured by chain, top view.
Source organism: Hydra vulgaris
Primary publication:
Annexin XII E105K crystal structure: identification of a pH-dependent switch for mutant hexamerization.
Cartailler JP, Haigler HT, Luecke H
Biochemistry 39 2475-83 (2000)
PMID: 10704197

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo hexamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-150682 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Annexin-B12 Chains: A, B, C, D, E, F
Molecule details ›
Chains: A, B, C, D, E, F
Length: 315 amino acids
Theoretical weight: 35.02 KDa
Source organism: Hydra vulgaris
Expression system: Escherichia coli
UniProt:
  • Canonical: P26256 (Residues: 2-316; Coverage: 100%)
Gene name: ANXB12
Sequence domains: Annexin
Structure domains: Annexin

Ligands and Environments

1 bound ligand:
Ligand CA 11 x CA
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL7-1
Spacegroup: P212121
Unit cell:
a: 68.943Å b: 162.544Å c: 188.798Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.236 0.208 0.263
Expression system: Escherichia coli

Quick links

Citations

1 review citation

Annexins: from structure to function.
Gerke et al. (2002)
12 other articles

4 mentions without citation

The role of hydrophobic interactions in positioning of peripheral proteins in membranes.
Lomize et al. (2007)
3 more