› 1dpr

X-ray diffraction
3Å resolution

STRUCTURES OF THE APO-AND METAL ION ACTIVATED FORMS OF THE DIPHTHERIA TOX REPRESSOR FROM CORYNEBACTERIUM DIPHTHERIAE

Released:
DOI: 10.2210/pdb1dpr/pdb
PDB entry 1dpr coloured by chain, front view.
PDB entry 1dpr coloured by chain, side view.
PDB entry 1dpr coloured by chain, top view.
Source organism: Corynebacterium diphtheriae
Primary publication:
Structures of the apo- and the metal ion-activated forms of the diphtheria tox repressor from Corynebacterium diphtheriae.
Schiering N, Tao X, Zeng H, Murphy JR, Petsko GA, Ringe D
Proc Natl Acad Sci U S A 92 9843-50 (1995)
PMID: 7568230

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-143594 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Diphtheria toxin repressor Chains: A, B
Molecule details ›
Chains: A, B
Length: 226 amino acids
Theoretical weight: 25.35 KDa
Source organism: Corynebacterium diphtheriae
Expression system: Escherichia coli
UniProt:
  • Canonical: P0DJL7 (Residues: 1-226; Coverage: 100%)
Gene names: DIP1414, dtxR
Sequence domains:
Structure domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: P3221
Unit cell:
a: 64Å b: 64Å c: 220.4Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.241 0.241 0.417
Expression system: Escherichia coli

Quick links

Citations

10 review citations

Bacterial iron sources: from siderophores to hemophores.
Wandersman et al. (2004)
9 more

2 mentions without citation

Mechanism of metal ion activation of the diphtheria toxin repressor DtxR.
D'Aquino et al. (2005)
1 more