› 1dsr

Solution NMR

Peptide antibiotic, NMR, 6 structures

Released:
DOI: 10.2210/pdb1dsr/pdb
PDB entry 1dsr coloured by chain, ensemble of 6 models, front view.
PDB entry 1dsr coloured by chain, ensemble of 6 models, side view.
PDB entry 1dsr coloured by chain, ensemble of 6 models, top view.
Source organism: Actinoplanes sp.
Primary publication:
3D structure of ramoplanin: a potent inhibitor of bacterial cell wall synthesis.
Kurz M, Guba W
Biochemistry 35 12570-5 (1996)
PMID: 8823194

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-162161 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (2 distinct):
RAMOPLANIN A2 Chain: A
Molecule details ›
Chain: A
Length: 17 amino acids
Theoretical weight: 2.11 KDa
Source organism: Actinoplanes sp.

Ligands and Environments

Carbohydrate polymer : NEW Components: MAN
Carbohydrate polymer
1 bound ligand:
Ligand FA7 1 x FA7
7 modified residues:
Ligand AHB 1 x AHB
Ligand GHP 2 x GHP
Ligand 2TL 2 x 2TL
Ligand D4P 3 x D4P
Ligand ALO 1 x ALO
Ligand DAL 1 x DAL
Ligand CHP 1 x CHP

Experiments and Validation Details

Entry percentile scores

Quick links

Citations

11 review citations

Molecular mechanisms that confer antibacterial drug resistance.
Walsh C. (2000)
10 more

2 mentions without citation

Complexation of peptidoglycan intermediates by the lipoglycodepsipeptide antibiotic ramoplanin: minimal structural requirements for intermolecular complexation and fibril formation.
Cudic et al. (2002)
1 more