› 1dua

X-ray diffraction
2Å resolution

CRYSTAL STRUCTURE OF EXFOLIATIVE TOXIN A

Released:
DOI: 10.2210/pdb1dua/pdb
PDB entry 1dua coloured by chain, front view.
PDB entry 1dua coloured by chain, side view.
PDB entry 1dua coloured by chain, top view.
Source organism: Staphylococcus aureus
Primary publication:
Structural similarities and differences in Staphylococcus aureus exfoliative toxins A and B as revealed by their crystal structures.
Papageorgiou AC, Plano LR, Collins CM, Acharya KR
Protein Sci 9 610-8 (2000)
PMID: 10752623

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-140613 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Exfoliative toxin A Chain: A
Molecule details ›
Chain: A
Length: 242 amino acids
Theoretical weight: 26.99 KDa
Source organism: Staphylococcus aureus
Expression system: Escherichia coli
UniProt:
  • Canonical: P09331 (Residues: 39-280; Coverage: 100%)
Gene name: eta
Sequence domains: Trypsin-like peptidase domain
Structure domains: Trypsin-like serine proteases

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SRS BEAMLINE PX9.6
Spacegroup: P21
Unit cell:
a: 47.138Å b: 67.228Å c: 47.999Å
α: 90° β: 118.09° γ: 90°
R-values:
R R work R free
0.214 0.214 0.252
Expression system: Escherichia coli

Quick links

Citations

5 review citations

Bacterial protease inhibitors.
Supuran et al. (2002)
4 more

1 mention without citation

Staphylococcus aureus Exfoliative Toxin E, Oligomeric State and Flip of P186: Implications for Its Action Mechanism.
Gismene et al. (2022)