› 1dzl

X-ray diffraction
3.5Å resolution

L1 protein of human papillomavirus 16

Released:
DOI: 10.2210/pdb1dzl/pdb
PDB entry 1dzl coloured by chain, front view.
PDB entry 1dzl coloured by chain, side view.
PDB entry 1dzl coloured by chain, top view.
Source organism: Human papillomavirus type 16
Primary publication:
Structure of small virus-like particles assembled from the L1 protein of human papillomavirus 16.
Chen XS, Garcea RL, Goldberg I, Casini G, Harrison SC
Mol Cell 5 557-67 (2000)
PMID: 10882140

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo 60-mer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-136576 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Major capsid protein L1 Chain: A
Molecule details ›
Chain: A
Length: 505 amino acids
Theoretical weight: 56.44 KDa
Source organism: Human papillomavirus type 16
Expression system: Escherichia coli
UniProt:
  • Canonical: P03101 (Residues: 1-505; Coverage: 100%)
Gene name: L1
Sequence domains: L1 (late) protein
Structure domains: Major capsid L1 (late) superfamily, Papillomavirus

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: CHESS BEAMLINE F2
Spacegroup: P213
Unit cell:
a: 387Å b: 387Å c: 387Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.28 0.28 0.29
Expression system: Escherichia coli

Quick links

Citations

68 review citations

Virus-like particles in vaccine development.
Roldão et al. (2010)
67 more

27 mentions without citation

Origins and evolution of viruses of eukaryotes: The ultimate modularity.
Koonin et al. (2015)
26 more