› 1e7z

X-ray diffraction
2.05Å resolution

Crystal structure of the EMAP2/RNA binding domain of the p43 protein from human aminoacyl-tRNA synthetase complex

Released:
DOI: 10.2210/pdb1e7z/pdb
PDB entry 1e7z coloured by chain, front view.
PDB entry 1e7z coloured by chain, side view.
PDB entry 1e7z coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Structure of the EMAPII domain of human aminoacyl-tRNA synthetase complex reveals evolutionary dimer mimicry.
Renault L, Kerjan P, Pasqualato S, Ménétrey J, Robinson JC, Kawaguchi S, Vassylyev DG, Yokoyama S, Mirande M, Cherfils J
EMBO J 20 570-8 (2001)
PMID: 11157763

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-171431 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Endothelial monocyte-activating polypeptide 2 Chain: A
Molecule details ›
Chain: A
Length: 174 amino acids
Theoretical weight: 19.3 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q12904 (Residues: 148-312; Coverage: 53%)
Gene names: AIMP1, EMAP2, SCYE1
Sequence domains: Putative tRNA binding domain
Structure domains: Nucleic acid-binding proteins

Ligands and Environments

1 bound ligand:
Ligand HG 2 x HG
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-1
Spacegroup: P21
Unit cell:
a: 36.141Å b: 53.938Å c: 41.371Å
α: 90° β: 111.92° γ: 90°
R-values:
R R work R free
0.221 0.221 0.272
Expression system: Escherichia coli

Quick links

Citations

9 review citations

Evolution of protein structures and functions.
Kinch et al. (2002)
8 more

1 mention without citation

Structure of the EMAPII domain of human aminoacyl-tRNA synthetase complex reveals evolutionary dimer mimicry.
Renault et al. (2001)