Function and Biology Details
Reactions catalysed:
GTP + H(2)O = GDP + phosphate
ATP + a protein = ADP + a phosphoprotein
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-158137 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Cell division control protein 42 homolog
Molecule details ›
Chain: A
Length: 178 amino acids
Theoretical weight: 19.77 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains: Ras family
Structure domains: P-loop containing nucleotide triphosphate hydrolases
Length: 178 amino acids
Theoretical weight: 19.77 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical:
P60953 (Residues: 1-178; Coverage: 93%)
Sequence domains: Ras family
Structure domains: P-loop containing nucleotide triphosphate hydrolases
Serine/threonine-protein kinase PAK 3
Molecule details ›
Chain: B
Length: 46 amino acids
Theoretical weight: 5.12 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
Sequence domains: P21-Rho-binding domain
Structure domains: CRIB domain
Length: 46 amino acids
Theoretical weight: 5.12 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
- Canonical: Q61036 (Residues: 65-123; Coverage: 8%)
Sequence domains: P21-Rho-binding domain
Structure domains: CRIB domain
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
Refinement method:
distance geometry simulated annealing Ramachandran refinement
Expression system: Escherichia coli
