› 1efo

X-ray diffraction
2.3Å resolution

CRYSTAL STRUCTURE OF AN ADENINE BULGE IN THE RNA CHAIN OF A DNA/RNA HYBRID, D(CTCCTCTTC)/R(GAAGAGAGAG)

Released:
DOI: 10.2210/pdb1efo/pdb
PDB entry 1efo coloured by chain, front view.
PDB entry 1efo coloured by chain, side view.
PDB entry 1efo coloured by chain, top view.
Source organism: Synthetic construct
Primary publication:
Crystal structure of an adenine bulge in the RNA chain of a DNA.RNA hybrid, d(CTCCTCTTC).r(gaagagagag).
Sudarsanakumar C, Xiong Y, Sundaralingam M
J Mol Biol 299 103-12 (2000)
PMID: 10860725

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
PDBe Complex ID:
PDB-CPX-113733 (preferred)
Entry contents:
1 distinct DNA molecule
1 distinct RNA molecule
Macromolecules (2 distinct):
DNA (5'-D(*CP*TP*CP*CP*TP*CP*TP*TP*C)-3') Chain: A
Molecule details ›
Chain: A
Length: 9 nucleotides
Theoretical weight: 2.62 KDa
Source organism: Synthetic construct
Expression system: Not provided
RNA (5'-R(*GP*AP*AP*GP*AP*GP*AP*GP*AP*G)-3') Chain: B
Molecule details ›
Chain: B
Length: 10 nucleotides
Theoretical weight: 3.33 KDa
Source organism: Synthetic construct
Expression system: Not provided

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU
Spacegroup: I222
Unit cell:
a: 46.66Å b: 47.61Å c: 54.04Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.199 0.199 0.222
Expression system: Not provided

Quick links

Citations

12 citation in other articles

Distinctive structural motifs of RNA G-quadruplexes composed of AGG, CGG and UGG trinucleotide repeats.
Malgowska et al. (2014)
11 more