› 1egp

X-ray diffraction
2Å resolution

PROTEINASE INHIBITOR EGLIN C WITH HYDROLYSED REACTIVE CENTER

Released:
DOI: 10.2210/pdb1egp/pdb
PDB entry 1egp coloured by chain, front view.
PDB entry 1egp coloured by chain, side view.
PDB entry 1egp coloured by chain, top view.
Source organism: Hirudo medicinalis
Primary publication:
Structure of the proteinase inhibitor eglin c with hydrolysed reactive centre at 2.0 A resolution.
Betzel C, Dauter Z, Genov N, Lamzin V, Navaza J, Schnebli HP, Visanji M, Wilson KS
FEBS Lett 317 185-8 (1993)
PMID: 8425603

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-133909 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Eglin C Chain: A
Molecule details ›
Chain: A
Length: 45 amino acids
Theoretical weight: 5.19 KDa
Source organism: Hirudo medicinalis
UniProt:
  • Canonical: P01051 (Residues: 1-45; Coverage: 64%)
Sequence domains: Potato inhibitor I family
Eglin C Chain: B
Molecule details ›
Chain: B
Length: 25 amino acids
Theoretical weight: 2.93 KDa
Source organism: Hirudo medicinalis
UniProt:
  • Canonical: P01051 (Residues: 46-70; Coverage: 36%)
Sequence domains: Potato inhibitor I family

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: P43
Unit cell:
a: 42Å b: 42Å c: 35Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.122 not available not available

Quick links

Citations

1 review citation

Proteinase inhibitors from the European medicinal leech Hirudo medicinalis: structural, functional and biomedical aspects.
Ascenzi et al. (1995)
7 other articles