› 1egt

Solution NMR

THROMBIN-BOUND STRUCTURE OF AN EGF SUBDOMAIN FROM HUMAN THROMBOMODULIN DETERMINED BY TRANSFERRED NUCLEAR OVERHAUSER EFFECTS

Released:
DOI: 10.2210/pdb1egt/pdb
PDB entry 1egt coloured by chain, ensemble of 3 models, front view.
PDB entry 1egt coloured by chain, ensemble of 3 models, side view.
PDB entry 1egt coloured by chain, ensemble of 3 models, top view.
Source organism: Homo sapiens
Primary publication:
Thrombin-bound structure of an EGF subdomain from human thrombomodulin determined by transferred nuclear Overhauser effects.
Srinivasan J, Hu S, Hrabal R, Zhu Y, Komives EA, Ni F
Biochemistry 33 13553-60 (1994)
PMID: 7947766

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
Sequence domain:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-139431 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Thrombomodulin Chain: A
Molecule details ›
Chain: A
Length: 17 amino acids
Theoretical weight: 1.91 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P07204 (Residues: 427-444; Coverage: 3%)
Gene names: THBD, THRM
Sequence domains: Complement Clr-like EGF-like

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Expression system: Not provided

Quick links

Citations

3 review citations

Thrombomodulin: from haemostasis to inflammation and tumourigenesis.
Koutsi et al. (2008)
2 more

1 mention without citation

The dipeptidyl peptidase IV inhibitors vildagliptin and K-579 inhibit a phospholipase C: a case of promiscuous scaffolds in proteins.
Chakraborty et al. (2013)