› 1ei0

Solution NMR

NMR STRUCTURE OF THE ALPHA-HELICAL HAIRPIN OF P8MTCP1

Released:
DOI: 10.2210/pdb1ei0/pdb
PDB entry 1ei0 coloured by chain, front view.
PDB entry 1ei0 coloured by chain, side view.
PDB entry 1ei0 coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Synthesis and NMR solution structure of an alpha-helical hairpin stapled with two disulfide bridges.
Barthe P, Rochette S, Vita C, Roumestand C
Protein Sci 9 942-55 (2000)
PMID: 10850804

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-157454 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Cx9C motif-containing protein 4 Chain: A
Molecule details ›
Chain: A
Length: 38 amino acids
Theoretical weight: 4.28 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P56277 (Residues: 5-42; Coverage: 56%)
Gene names: C6.1B, CMC4, MTCP1, MTCP1NB
Sequence domains: Mature-T-Cell Proliferation I type

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: distance geometry, molecular dynamics
Expression system: Not provided

Quick links

Citations

2 review citations

Hydrocarbon-stapled peptides: principles, practice, and progress.
Walensky et al. (2014)
1 more

3 mentions without citation

Stapled Peptides Inhibitors: A New Window for Target Drug Discovery.
Ali et al. (2019)
2 more