› 1emz

Solution NMR

SOLUTION STRUCTURE OF FRAGMENT (350-370) OF THE TRANSMEMBRANE DOMAIN OF HEPATITIS C ENVELOPE GLYCOPROTEIN E1

Released:
DOI: 10.2210/pdb1emz/pdb
PDB entry 1emz coloured by chain, front view.
PDB entry 1emz coloured by chain, side view.
PDB entry 1emz coloured by chain, top view.
Source organism: Hepacivirus C
Primary publication:
The transmembrane domains of hepatitis C virus envelope glycoproteins E1 and E2 play a major role in heterodimerization.
Op De Beeck A, Montserret R, Duvet S, Cocquerel L, Cacan R, Barberot B, Le Maire M, Penin F, Dubuisson J
J Biol Chem 275 31428-37 (2000)
PMID: 10807921

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
Sequence domain:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-192973 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
ENVELOPE GLYCOPROTEIN E1 Chain: A
Molecule details ›
Chain: A
Length: 21 amino acids
Theoretical weight: 2.24 KDa
Source organism: Hepacivirus C
Expression system: Not provided
UniProt:
  • Canonical: Q9Q3N3 (Residues: 22-42; Coverage: 26%)
Sequence domains: Hepatitis C virus envelope glycoprotein E1

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: distance geometry, simulated annealing, molecular dynamic, energy minimization
Expression system: Not provided

Quick links

Citations

22 review citations

Structural biology of hepatitis C virus.
Penin et al. (2004)
21 more

6 mentions without citation

Role of Hepatitis C Virus Envelope Glycoprotein E1 in Virus Entry and Assembly.
Tong et al. (2018)
5 more