› 1enf

X-ray diffraction
1.69Å resolution

CRYSTAL STRUCTURE OF STAPHYLOCOCCAL ENTEROTOXIN H DETERMINED TO 1.69 A RESOLUTION

Released:
DOI: 10.2210/pdb1enf/pdb
PDB entry 1enf coloured by chain, front view.
PDB entry 1enf coloured by chain, side view.
PDB entry 1enf coloured by chain, top view.
Source organism: Staphylococcus aureus
Primary publication:
The crystal structure of staphylococcal enterotoxin H: implications for binding properties to MHC class II and TcR molecules.
Hâkansson M, Petersson K, Nilsson H, Forsberg G, Björk P, Antonsson P, Svensson LA
J Mol Biol 302 527-37 (2000)
PMID: 10986116

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domains:

Structure analysis Details

Assemblies composition:
monomeric (preferred)
homo hexamer
homo trimer
Assembly name:
PDBe Complex ID:
PDB-CPX-140949 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Enterotoxin type H Chain: A
Molecule details ›
Chain: A
Length: 212 amino acids
Theoretical weight: 24.56 KDa
Source organism: Staphylococcus aureus
Expression system: Escherichia coli
UniProt:
  • Canonical: P0A0M0 (Residues: 26-237; Coverage: 98%)
Gene names: entH, seh
Sequence domains:
Structure domains:

Ligands and Environments

1 bound ligand:
Ligand SO4 13 x SO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: MAX II BEAMLINE I711
Spacegroup: R32
Unit cell:
a: 84.85Å b: 84.85Å c: 223.59Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.164 0.164 0.187
Expression system: Escherichia coli

Quick links

Citations

10 review citations

Toxic shock syndrome and bacterial superantigens: an update.
McCormick et al. (2001)
9 more

3 mentions without citation

Crystal structure of a superantigen bound to MHC class II displays zinc and peptide dependence.
Petersson et al. (2001)
2 more