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› 1epu

X-ray diffraction
2.4Å resolution

X-RAY crystal structure of neuronal SEC1 from squid

Released:
DOI: 10.2210/pdb1epu/pdb
Model geometry
Fit model/data
PDB entry 1epu coloured by chain, front view.
PDB entry 1epu coloured by chain, side view.
PDB entry 1epu coloured by chain, top view.
Source organism: Doryteuthis pealeii
Primary publication:
The X-ray crystal structure of neuronal Sec1 from squid sheds new light on the role of this protein in exocytosis.
Bracher A, Perrakis A, Dresbach T, Betz H, Weissenhorn W
Structure 8 685-94 (2000)
PMID: 10903948

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-130257 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Sec1-like protein Chain: A
Molecule details ›
Chain: A
Length: 591 amino acids
Theoretical weight: 68.82 KDa
Source organism: Doryteuthis pealeii
Expression system: Escherichia coli
UniProt:
  • Canonical: O62547 (Residues: 1-591; Coverage: 100%)
Sequence domains: Sec1 family
Structure domains:

Ligands and Environments

No bound ligands
1 modified residue:
Ligand MSE 21 x MSE

Experiments and Validation Details

wwPDB Validation report is not available for this entry.
X-ray source: ESRF BEAMLINE ID14-4
Spacegroup: P21
Unit cell:
a: 49.063Å b: 121.989Å c: 69.046Å
α: 90° β: 104.53° γ: 90°
R-values:
R R work R free
0.251 0.24 0.277
Expression system: Escherichia coli

Quick links

Citations

5 review citations

Snares and Munc18 in synaptic vesicle fusion.
Rizo et al. (2002)
4 more

8 mentions without citation

Structural basis for the Golgi membrane recruitment of Sly1p by Sed5p.
Bracher et al. (2002)
7 more