› 1eq9

X-ray diffraction
1.7Å resolution

CRYSTAL STRUCTURE OF FIRE ANT CHYMOTRYPSIN COMPLEXED TO PMSF

Released:
DOI: 10.2210/pdb1eq9/pdb
PDB entry 1eq9 coloured by chain, front view.
PDB entry 1eq9 coloured by chain, side view.
PDB entry 1eq9 coloured by chain, top view.
Source organism: Solenopsis invicta
Primary publication:
The structure of an insect chymotrypsin.
Botos I, Meyer E, Nguyen M, Swanson SM, Koomen JM, Russell DH, Meyer EF
J. Mol. Biol. 298 895-901 (2000)
PMID: 10801356

Function and Biology Details

Reaction catalysed: 
Preferential cleavage: Tyr-|-Xaa, Trp-|-Xaa, Phe-|-Xaa, Leu-|-Xaa.
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-181978 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Chymotrypsin-1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 222 amino acids
Theoretical weight: 24.04 KDa
Source organism: Solenopsis invicta
UniProt:
  • Canonical: Q7SIG2 (Residues: 1-222; Coverage: 100%)
Sequence domains: Trypsin
Structure domains: Trypsin-like serine proteases

Ligands and Environments

1 bound ligand:
Ligand PMS 2 x PMS
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RU200
Spacegroup: P212121
Unit cell:
a: 61.12Å b: 85.84Å c: 97.61Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.209 0.209 0.242

Quick links

Citations

1 review citation

Structural and functional diversities in lepidopteran serine proteases.
Srinivasan et al. (2006)
18 other articles

12 mentions without citation

Selection on Glycine beta-1,3-endoglucanase genes differentially inhibited by a Phytophthora glucanase inhibitor protein.
Bishop et al. (2005)
11 more