› 1es6

X-ray diffraction
2Å resolution

CRYSTAL STRUCTURE OF THE MATRIX PROTEIN OF EBOLA VIRUS

Released:
DOI: 10.2210/pdb1es6/pdb
PDB entry 1es6 coloured by chain, front view.
PDB entry 1es6 coloured by chain, side view.
PDB entry 1es6 coloured by chain, top view.
Source organism: Ebola virus sp.
Primary publication:
Crystal structure of the matrix protein VP40 from Ebola virus.
Dessen A, Volchkov V, Dolnik O, Klenk HD, Weissenhorn W
EMBO J 19 4228-36 (2000)
PMID: 10944105

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-181208 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Matrix protein VP40 Chain: A
Molecule details ›
Chain: A
Length: 296 amino acids
Theoretical weight: 31.86 KDa
Source organism: Ebola virus sp.
Expression system: Escherichia coli
UniProt:
  • Canonical: Q77DJ6 (Residues: 31-326; Coverage: 91%)
Gene name: VP40
Sequence domains: Matrix protein VP40
Structure domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE BM14
Spacegroup: C2
Unit cell:
a: 64.637Å b: 91.094Å c: 49.226Å
α: 90° β: 97.35° γ: 90°
R-values:
R R work R free
0.223 0.22 0.25
Expression system: Escherichia coli

Quick links

Citations

23 review citations

Filovirus assembly and budding.
Hartlieb et al. (2006)
22 more

17 mentions without citation

Paramyxovirus assembly and budding: building particles that transmit infections.
Harrison et al. (2010)
16 more