Function and Biology Details
Reactions catalysed:
Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1)
Selective cleavage of Gln-|-Gly bond in the poliovirus polyprotein. In other picornavirus reactions Glu may be substituted for Gln, and Ser or Thr for Gly.
Selective cleavage of Tyr-|-Gly bond in picornavirus polyprotein.
NTP + H(2)O = NDP + phosphate
Biochemical function:
Biological process:
- not assigned
Cellular component:
Structure analysis Details
Assembly composition:
hetero 240-mer (preferred)
Assembly name:
Capsid protein VP4 (preferred)
PDBe Complex ID:
PDB-CPX-131643 (preferred)
Entry contents:
4 distinct polypeptide molecules
Macromolecules (4 distinct):
Capsid protein VP1
Molecule details ›
Chain: 1
Length: 281 amino acids
Theoretical weight: 31.6 KDa
Source organism: Echovirus E1
UniProt:
Structure domains: Jelly Rolls
Length: 281 amino acids
Theoretical weight: 31.6 KDa
Source organism: Echovirus E1
UniProt:
- Canonical:
O91734 (Residues: 570-850; Coverage: 13%)
Structure domains: Jelly Rolls
Capsid protein VP2
Molecule details ›
Chain: 2
Length: 254 amino acids
Theoretical weight: 28.13 KDa
Source organism: Echovirus E1
UniProt:
Structure domains: Jelly Rolls
Length: 254 amino acids
Theoretical weight: 28.13 KDa
Source organism: Echovirus E1
UniProt:
- Canonical: O91734 (Residues: 77-330; Coverage: 12%)
Structure domains: Jelly Rolls
Capsid protein VP3
Molecule details ›
Chain: 3
Length: 239 amino acids
Theoretical weight: 26.47 KDa
Source organism: Echovirus E1
UniProt:
Structure domains: Jelly Rolls
Length: 239 amino acids
Theoretical weight: 26.47 KDa
Source organism: Echovirus E1
UniProt:
- Canonical: O91734 (Residues: 331-569; Coverage: 11%)
Structure domains: Jelly Rolls
Capsid protein VP4
Molecule details ›
Chain: 4
Length: 68 amino acids
Theoretical weight: 7.4 KDa
Source organism: Echovirus E1
UniProt:
Structure domains: Picornavirus coat protein VP4
Length: 68 amino acids
Theoretical weight: 7.4 KDa
Source organism: Echovirus E1
UniProt:
- Canonical: O91734 (Residues: 2-69; Coverage: 3%)
Structure domains: Picornavirus coat protein VP4
