› 1exy

Solution NMR

SOLUTION STRUCTURE OF HTLV-1 PEPTIDE BOUND TO ITS RNA APTAMER TARGET

Released:
DOI: 10.2210/pdb1exy/pdb
PDB entry 1exy coloured by chain, ensemble of 12 models, front view.
PDB entry 1exy coloured by chain, ensemble of 12 models, side view.
PDB entry 1exy coloured by chain, ensemble of 12 models, top view.
Source organisms:
Primary publication:
Anchoring an extended HTLV-1 Rex peptide within an RNA major groove containing junctional base triples.
Jiang F, Gorin A, Hu W, Majumdar A, Baskerville S, Xu W, Ellington A, Patel DJ
Structure 7 1461-72 (1999)
PMID: 10647177

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Structure domain:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-142984 (preferred)
Entry contents:
1 distinct polypeptide molecule
1 distinct RNA molecule
Macromolecules (2 distinct):
Protein Rex Chain: B
Molecule details ›
Chain: B
Length: 16 amino acids
Theoretical weight: 2.12 KDa
Source organism: Human T-cell leukemia virus type I
Expression system: Not provided
UniProt:
  • Canonical: P0C206 (Residues: 1-16; Coverage: 9%)
RNA APTAMER, 33-MER Chain: A
Molecule details ›
Chain: A
Length: 33 nucleotides
Theoretical weight: 10.65 KDa
Source organism: Human T-cell lymphotrophic virus type 1 (Caribbean isolate)
Expression system: Not provided

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: simulated annealing with torsion angle dynamics
Expression system: Not provided

Quick links

Citations

7 review citations

RNA bulges as architectural and recognition motifs.
Hermann et al. (2000)
6 more

5 mentions without citation

Deep structural insights into RNA-binding disordered protein regions.
Zeke et al. (2022)
4 more