We've built a new version of this page with an interactive 3D viewer. Try it out in beta and help us improve:

› 1f6j

X-ray diffraction
2.25Å resolution

CRYSTAL STRUCTURE OF THE E-DNA HEXAMER GGCGBR5CC

Released:
DOI: 10.2210/pdb1f6j/pdb
Model geometry
Fit model/data
Data not analysed
PDB entry 1f6j coloured by chain, front view.
PDB entry 1f6j coloured by chain, side view.
PDB entry 1f6j coloured by chain, top view.
Source organism: Synthetic construct
Primary publication:
The extended and eccentric E-DNA structure induced by cytosine methylation or bromination.
Vargason JM, Eichman BF, Ho PS
Nat Struct Biol 7 758-61 (2000)
PMID: 10966645

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-113797 (preferred)
Entry contents:
1 distinct DNA molecule
Macromolecule:
DNA (5'-D(*GP*GP*CP*GP*(CBR)P*C)-3') Chains: A, B
Molecule details ›
Chains: A, B
Length: 6 nucleotides
Theoretical weight: 1.89 KDa
Source organism: Synthetic construct
Expression system: Not provided

Ligands and Environments

No bound ligands
1 modified residue:
Ligand CBR 2 x CBR

Experiments and Validation Details

wwPDB Validation report is not available for this entry.
X-ray source: RIGAKU RU300
Spacegroup: P43212
Unit cell:
a: 60.4Å b: 60.4Å c: 24.704Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.2 0.193 0.256
Expression system: Not provided

Quick links

Citations

6 review citations

Demethylation of (Cytosine-5-C-methyl) DNA and regulation of transcription in the epigenetic pathways of cancer development.
Patra et al. (2008)
5 more