› 1f6r

X-ray diffraction
2.2Å resolution

CRYSTAL STRUCTURE OF APO-BOVINE ALPHA-LACTALBUMIN

Released:
DOI: 10.2210/pdb1f6r/pdb
PDB entry 1f6r coloured by chain, front view.
PDB entry 1f6r coloured by chain, side view.
PDB entry 1f6r coloured by chain, top view.
Source organism: Bos taurus
Primary publication:
Crystal structures of apo- and holo-bovine alpha-lactalbumin at 2. 2-A resolution reveal an effect of calcium on inter-lobe interactions.
Chrysina ED, Brew K, Acharya KR
J Biol Chem 275 37021-9 (2000)
PMID: 10896943

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo hexamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-132934 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Alpha-lactalbumin Chains: A, B, C, D, E, F
Molecule details ›
Chains: A, B, C, D, E, F
Length: 123 amino acids
Theoretical weight: 14.2 KDa
Source organism: Bos taurus
UniProt:
  • Canonical: P00711 (Residues: 20-142; Coverage: 100%)
Gene names: ALACTA, LALBA
Sequence domains: C-type lysozyme/alpha-lactalbumin family
Structure domains: Lysozyme

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SRS BEAMLINE PX9.5
Spacegroup: P41212
Unit cell:
a: 119.568Å b: 119.568Å c: 152.745Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.191 0.191 0.248

Quick links

Citations

2 review citations

Bioactivity of α-lactalbumin related to its interaction with fatty acids: a review.
Barbana et al. (2011)
1 more

20 mentions without citation

Relevant B cell epitopes in allergic disease.
Pomés A. (2010)
19 more