› 1f8p

Solution NMR

PORCINE NEUROPEPTIDE Y BOUND TO DPC MICELLES

Released:
DOI: 10.2210/pdb1f8p/pdb
PDB entry 1f8p coloured by chain, ensemble of 17 models, front view.
PDB entry 1f8p coloured by chain, ensemble of 17 models, side view.
PDB entry 1f8p coloured by chain, ensemble of 17 models, top view.
Source organism: Sus scrofa
Primary publication:
Structure and dynamics of micelle-bound neuropeptide Y: comparison with unligated NPY and implications for receptor selection.
Bader R, Bettio A, Beck-Sickinger AG, Zerbe O
J Mol Biol 305 307-29 (2001)
PMID: 11124908

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-134180 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Neuropeptide Y Chain: A
Molecule details ›
Chain: A
Length: 37 amino acids
Theoretical weight: 4.26 KDa
Source organism: Sus scrofa
Expression system: Not provided
UniProt:
  • Canonical: P01304 (Residues: 10-45; Coverage: 54%)
Gene name: NPY
Sequence domains: Pancreatic hormone peptide

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: simmulated annealing in torsion angle space
Expression system: Not provided

Quick links

Citations

16 review citations

Long-lasting target binding and rebinding as mechanisms to prolong in vivo drug action.
Vauquelin et al. (2010)
15 more

2 mentions without citation

Illuminating the life of GPCRs.
Böhme et al. (2009)
1 more