› 1fad

Solution NMR

DEATH DOMAIN OF FAS-ASSOCIATED DEATH DOMAIN PROTEIN, RESIDUES 89-183

Released:
DOI: 10.2210/pdb1fad/pdb
PDB entry 1fad coloured by chain, ensemble of 21 models, front view.
PDB entry 1fad coloured by chain, ensemble of 21 models, side view.
PDB entry 1fad coloured by chain, ensemble of 21 models, top view.
Source organism: Mus musculus
Primary publication:
The solution structure of FADD death domain. Structural basis of death domain interactions of Fas and FADD.
Jeong EJ, Bang S, Lee TH, Park YI, Sim WS, Kim KS
J Biol Chem 274 16337-42 (1999)
PMID: 10347191

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-178862 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
FAS-associated death domain protein Chain: A
Molecule details ›
Chain: A
Length: 99 amino acids
Theoretical weight: 11.09 KDa
Source organism: Mus musculus
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q61160 (Residues: 88-183; Coverage: 47%)
Gene names: Fadd, Mort1
Sequence domains: Death domain
Structure domains: Death Domain, Fas

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: DISTANCE GEOMETRY AND SIMMULATED ANNEALING
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

20 review citations

Death receptor-induced cell killing.
Thorburn A. (2004)
19 more

7 mentions without citation

The PYRIN domain in signal transduction.
Stehlik C. (2007)
6 more