› 1faf

Solution NMR

NMR STRUCTURE OF THE N-TERMINAL J DOMAIN OF MURINE POLYOMAVIRUS T ANTIGENS.

Released:
DOI: 10.2210/pdb1faf/pdb
PDB entry 1faf coloured by chain, ensemble of 47 models, front view.
PDB entry 1faf coloured by chain, ensemble of 47 models, side view.
PDB entry 1faf coloured by chain, ensemble of 47 models, top view.
Source organism: Mus musculus polyomavirus 1
Primary publication:
NMR structure of the N-terminal J domain of murine polyomavirus T antigens. Implications for DnaJ-like domains and for mutations of T antigens.
Berjanskii MV, Riley MI, Xie A, Semenchenko V, Folk WR, Van Doren SR
J Biol Chem 275 36094-103 (2000)
PMID: 10950962

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-136546 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Large T antigen Chain: A
Molecule details ›
Chain: A
Length: 79 amino acids
Theoretical weight: 9.18 KDa
Source organism: Mus musculus polyomavirus 1
Expression system: Escherichia coli
UniProt:
  • Canonical: P03073 (Residues: 1-79; Coverage: 10%)
Structure domains: DnaJ domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this NMR entry.
Refinement method: TORSION ANGLE DYNAMICS AND SIMULATED ANNEALING IN CARTESIAN SPACE
Expression system: Escherichia coli

Quick links

Citations

6 review citations

SV40 large T antigen targets multiple cellular pathways to elicit cellular transformation.
Ahuja et al. (2005)
5 more

7 mentions without citation

T antigens of simian virus 40: molecular chaperones for viral replication and tumorigenesis.
Sullivan et al. (2002)
6 more