› 1fja

Solution NMR

NMR STUDY OF DEOXYRIBONUCLEIC ACID COMPLEXED WITH ACTINOMYCIN D

Released:
DOI: 10.2210/pdb1fja/pdb
PDB entry 1fja coloured by chain, ensemble of 5 models, front view.
PDB entry 1fja coloured by chain, ensemble of 5 models, side view.
PDB entry 1fja coloured by chain, ensemble of 5 models, top view.
Source organism: Streptomyces antibioticus
Primary publication:
DNA bending and unwinding associated with actinomycin D antibiotics bound to partially overlapping sites on DNA.
Chen H, Liu X, Patel DJ
J Mol Biol 258 457-79 (1996)
PMID: 8642603

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero tetramer (preferred)
PDBe Complex ID:
PDB-CPX-113806 (preferred)
Entry contents:
1 distinct polypeptide molecule
1 distinct DNA molecule
Macromolecules (2 distinct):
ACTINOMYCIN D Chains: C, D
Molecule details ›
Chains: C, D
Length: 11 amino acids
Theoretical weight: 1.26 KDa
Source organism: Streptomyces antibioticus
Expression system: Not provided
DNA (5'-D(*AP*AP*GP*CP*GP*CP*TP*T)-3') Chains: A, B
Molecule details ›
Chains: A, B
Length: 8 nucleotides
Theoretical weight: 2.43 KDa
Source organism: Streptomyces antibioticus
Expression system: Not provided

Ligands and Environments

No bound ligands
3 modified residues:
Ligand DVA 4 x DVA
Ligand SAR 4 x SAR
Ligand MVA 4 x MVA

Experiments and Validation Details

Entry percentile scores
Expression system: Not provided

Quick links

Citations

2 review citations

Unusual DNA duplex and hairpin motifs.
Chou et al. (2003)
1 more