› 1fje

Solution NMR

SOLUTION STRUCTURE OF NUCLEOLIN RBD12 IN COMPLEX WITH SNRE RNA

Released:
DOI: 10.2210/pdb1fje/pdb
PDB entry 1fje coloured by chain, ensemble of 19 models, front view.
PDB entry 1fje coloured by chain, ensemble of 19 models, side view.
PDB entry 1fje coloured by chain, ensemble of 19 models, top view.
Source organism: Mesocricetus auratus
Primary publication:
Molecular basis of sequence-specific recognition of pre-ribosomal RNA by nucleolin.
Allain FH, Bouvet P, Dieckmann T, Feigon J
EMBO J 19 6870-81 (2000)
PMID: 11118222

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-140022 (preferred)
Entry contents:
1 distinct polypeptide molecule
1 distinct RNA molecule
Macromolecules (2 distinct):
Nucleolin Chain: B
Molecule details ›
Chain: B
Length: 175 amino acids
Theoretical weight: 19.37 KDa
Source organism: Mesocricetus auratus
Expression system: Escherichia coli
UniProt:
  • Canonical: P08199 (Residues: 295-469; Coverage: 25%)
Gene name: NCL
Sequence domains: RNA recognition motif
Structure domains: Alpha-Beta Plaits
SNRE RNA Chain: A
Molecule details ›
Chain: A
Length: 22 nucleotides
Theoretical weight: 7.1 KDa
Source organism: Mesocricetus auratus
Expression system: Not provided

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: simulated annealing using XPLOR 3.841
Expression systems:
  • Escherichia coli
  • Not provided

Quick links

Citations

30 review citations

Mechanisms of alternative pre-messenger RNA splicing.
Black DL. (2003)
29 more

6 mentions without citation

RNA sequence- and shape-dependent recognition by proteins in the ribonucleoprotein particle.
Stefl et al. (2005)
5 more