› 1fnl

X-ray diffraction
1.8Å resolution

CRYSTAL STRUCTURE OF THE EXTRACELLULAR DOMAIN OF A HUMAN FCGRIII

Released:
DOI: 10.2210/pdb1fnl/pdb
PDB entry 1fnl coloured by chain, front view.
PDB entry 1fnl coloured by chain, side view.
PDB entry 1fnl coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Crystal structure of the extracellular domain of a human Fc gamma RIII.
Zhang Y, Boesen CC, Radaev S, Brooks AG, Fridman WH, Sautes-Fridman C, Sun PD
Immunity 13 387-95 (2000)
PMID: 11021536

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-130815 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Low affinity immunoglobulin gamma Fc region receptor III-B Chain: A
Molecule details ›
Chain: A
Length: 175 amino acids
Theoretical weight: 20 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: O75015 (Residues: 19-192; Coverage: 80%)
Gene names: CD16B, FCG3, FCGR3, FCGR3B, IGFR3
Sequence domains: Immunoglobulin domain
Structure domains: Immunoglobulins

Ligands and Environments

1 bound ligand:
Ligand HG 2 x HG
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU
Spacegroup: P21212
Unit cell:
a: 67.427Å b: 85.733Å c: 36.33Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.184 0.184 0.216
Expression system: Escherichia coli

Quick links

Citations

20 review citations

Fcgamma receptors as regulators of immune responses.
Nimmerjahn et al. (2008)
19 more

10 mentions without citation

Radiation damage and derivatization in macromolecular crystallography: a structure factor's perspective.
Owen et al. (2016)
9 more