› 1fnn

X-ray diffraction
2Å resolution

CRYSTAL STRUCTURE OF CDC6P FROM PYROBACULUM AEROPHILUM

Released:
DOI: 10.2210/pdb1fnn/pdb
PDB entry 1fnn coloured by chain, front view.
PDB entry 1fnn coloured by chain, side view.
PDB entry 1fnn coloured by chain, top view.
Source organism: Pyrobaculum aerophilum
Primary publication:
Structure and function of Cdc6/Cdc18: implications for origin recognition and checkpoint control.
Liu J, Smith CL, DeRyckere D, DeAngelis K, Martin GS, Berger JM
Mol Cell 6 637-48 (2000)
PMID: 11030343

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:
Structure domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-187433 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
ORC1-type DNA replication protein Chains: A, B
Molecule details ›
Chains: A, B
Length: 389 amino acids
Theoretical weight: 44.26 KDa
Source organism: Pyrobaculum aerophilum
Expression system: Escherichia coli
UniProt:
  • Canonical: Q8ZYK1 (Residues: 1-389; Coverage: 100%)
Gene name: PAE0737
Sequence domains:
Structure domains:

Ligands and Environments

2 bound ligands:
Ligand MG 2 x MG
Ligand ADP 2 x ADP
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 5.0.2
Spacegroup: P31
Unit cell:
a: 132.07Å b: 132.07Å c: 82.2Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.221 0.221 0.257
Expression system: Escherichia coli

Quick links

Citations

47 review citations

DNA replication in eukaryotic cells.
Bell et al. (2002)
46 more

25 mentions without citation

NLRP3 inflammasome: from a danger signal sensor to a regulatory node of oxidative stress and inflammatory diseases.
Abderrazak et al. (2015)
24 more